Webinar Archive

Welcome to the webinar archive, which features presentations about current scientific and policy topics related to computational and in vitro toxicology. These videos are recorded as part of the ASCCT/ESTIV monthly webinar series, sponsored by ASCCT and the European Society for Toxicology In Vitro. They are organized by year using the horizontal menu below. Please feel free to view any webinar; you can search for key words in the search bar at the top of the page.

You can also view all of the webinars on our YouTube channel.

To find out about the next webinar, visit the calendar of events on the right side of the screen.

Finally, if you have ideas for upcoming webinars, please share them in the member Community Forum or by emailing [email protected].

2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016-2015 | 2014-2011

2023 Webinars

ASCCT Award Winners Webinar (January 2023)

Presenters:
Amber Daniel, M.S., Inotiv (slides)
Sunggun Lee, Duke University (slides)

Additional resources:

Li T, Tong W, Roberts R, Liu Z, Thakkar S. DeepCarc: Deep Learning-Powered Carcinogenicity Prediction Using Model-Level Representation. Front Artif Intell. 2021 Nov 18;4:757780. doi: 10.3389/frai.2021.757780. Erratum in: Front Artif Intell. 2022 Nov 28;5:1046668. PMID: 34870186; PMCID: PMC8636933.

Li T, Tong W, Roberts R, Liu Z, Thakkar S. DeepDILI: Deep Learning-Powered Drug-Induced Liver Injury Prediction Using Model-Level Representation. Chem Res Toxicol. 2021 Feb 15;34(2):550-565. doi: 10.1021/acs.chemrestox.0c00374. Epub 2020 Dec 23. PMID: 33356151.

Gaining Confidence in Advanced Methodologies for Studying Challenging Chemicals (February 2023)

Presenters:
Jesse Rogers, PhD, US Environmental Protection Agency (slides)
Kelly Carstens, PhD, US Environmental Protection Agency (slides)
Anna van der Zalm, MChem, PETA Science Consortium International (slides)

Award winners webinar: New approach methodologies for evaluating cardio- and developmental toxicity (March 2023)
Presenters:
Erika Ferrari, PhD, BiomimX Srl (slides)
Yanying Ma, National Food Institute, Technical University of Denmark (slides)

Modeling of Adverse Outcomes - Insights from the ONTOX Project (April 2023)

Presenters:
Devon Barnes, Utrecht Institute for Pharmaceutical Sciences Experimental Pharmacology group (slides)
Job Berkhout, RIVM (slides)

The Latest in Liver Toxicity Assessment In Vitro (May 2023)

Presenters:
Magnus Ingelman-Sundberg, PhD; BSc.Med, Karolinska Institutet
Mathieu Vinken, PhD, PharmD, ERT, Vrije Universiteit Brussel

PARC Consortium and Human Biomonitoring (May 2023)

Presenters:
Greet Schoeters, PhD, University of Antwerp (slides)
Mirjam Luijten, PhD, RIVM, EPAA Workgroup (slides)

The New OECD (Q)SAR Assessment Framework: Details and Examples (October 2023)

Presenters: Olga Tcheremenskaia, PhD, Istituto Superiore di Sanità (ISS) (Slides)
Andrea Gissi, PhD, European Chemicals Agency (ECHA) (Slides)
Patience Browne, PhD, Organisation for Economic Co-operation and Development (OECD) (Slides)

The Role of Mixtures for Effect-based Trigger Values in Water Quality Assessment (November 14, 2023)

Presenter: Beate Escher, PhD, Department Cell Toxicology, Helmholtz Centre for Environmental Research – UFZ, Leipzig, Germany

Application of Cell Painting for Chemical Hazard Evaluation in Support of Screening-level Assessments (November 27, 2023 - originally scheduled for September 2023)

Presenter: Jo Nyffeler, PhD, Helmholtz Centre for Environmental Research (UFZ) (Slides)

Additional Resources:

Nyffeler J, Willis C, Lougee R, Richard A, Paul-Friedman K, Harrill JA. Bioactivity screening of environmental chemicals using imaging-based high-throughput phenotypic profiling. Toxicology and Applied Pharmacology. 2020 Jan 15;389:114876. doi: 10.1016/j.taap.2019.114876. Epub 2019 Dec 30. PMID: 31899216; PMCID: PMC8409064.

Willis C, Nyffeler J, Harrill J. Phenotypic Profiling of Reference Chemicals across Biologically Diverse Cell Types Using the Cell Painting Assay. SLAS Discovery. 2020 Aug;25(7):755-769. doi: 10.1177/2472555220928004. Epub 2020 Jun 17. PMID: 32546035; PMCID: PMC9710725.

Nyffeler J, Haggard DE, Willis C, Setzer RW, Judson R, Paul-Friedman K, Everett LJ, Harrill JA. Comparison of Approaches for Determining Bioactivity Hits from High-Dimensional Profiling Data. SLAS Discovery. 2021 Feb;26(2):292-308. doi: 10.1177/2472555220950245. Epub 2020 Aug 29. PMID: 32862757; PMCID: PMC8673120.

Nyffeler J, Willis C, Harris FR, Taylor LW, Judson R, Everett LJ, Harrill JA. Combining phenotypic profiling and targeted RNA-Seq reveals linkages between transcriptional perturbations and chemical effects on cell morphology: Retinoic acid as an example. Toxicology and Applied Pharmacology. 2022 Jun 1;444:116032. doi: 10.1016/j.taap.2022.116032. Epub 2022 Apr 26. PMID: 35483669.

Nyffeler J, Willis C, Harris FR, Foster MJ, Chambers B, Culbreth M, Brockway RE, Davidson-Fritz S, Dawson D, Shah I, Friedman KP, Chang D, Everett LJ, Wambaugh JF, Patlewicz G, Harrill JA. Application of Cell Painting for chemical hazard evaluation in support of screening-level chemical assessments. Toxicology and Applied Pharmacology. 2023 Jun 1;468:116513. doi: 10.1016/j.taap.2023.116513. Epub 2023 Apr 11. PMID: 37044265.

ASCCT-ESTIV and JSAAE Joint Webinar: Accurate Evaluation of Hepatocyte Metabolisms on a Novel Oxygen-Permeable Material with Low Sorption Characteristics (December 11, 2023)

Presenter: Masaki Nishikawa, PhD, Department of Chemical System Engineering, University of Tokyo, Tokyo, Japan (Slides)