11th Annual Meeting of the ASCCT

Wednesday October 19, 2022 12:00PM through Friday October 21, 2022 12:30PM



We hope you will join us for the first in-person meeting in three years. The meeting will offer presentations, discussions, and other activities to support scientists, regulators, and stakeholders in the practice of in vitro, computational, and new approach toxicology. Students and early-career scientists interested in these fields are especially encouraged to attend. 


Meeting Features


We are excited to announce the following confirmed plenary speakers:

  • Gavin Maxwell, Unilever
  • Cavin Ward-Caviness, US EPA
  • Prof. Ellen Fritsche, IUF - Leibniz Research Institute of Environmental Medicine
  • Katie Paul-Friedman, US EPA
  • Tim Shafer, US EPA
  • Heather Stapleton, Duke University
  • Dan VIlleneuve, US EPA

Oral presentation sessions include:

  • Next Generation Risk Assessment
  • Decision-Making with NAMs
  • Developmental Neurotoxicity
  • Human Data for WoE Toxicology
  • Integrated Approaches to Testing and Assessment
  • Ecotoxicology

The meeting will feature the latest science in New Approach Methodologies and active discussions about the implementation of new science. The organizing committee is also planning fun activities, including a reception, science slam, expert panel, games, and maybe even a dance battle.

Students and early career scientists are especially encouraged to attend and present. The meeting will offer awards for students and early-career scientists, mentoring opportunities, and a continuing education course.

A virtual participation option is available, though we prefer that presenters are able to attend the event in person, barring extenuating circumstances. 

Please visit the online meeting program for the most updated information as well as logistical details and speaker instructions.



  • Registration for in-person attendance and online attendance is now open. Register here.
  • Registration deadline for in-person attendance is October 11th. If you are a presenter, please register by September 19th to confirm your attendance and intention to participate. Your timely registration permits advance planning and is appreciated.
  • If you wish to attend in person after October 7th, please contact info@ascctox.org

Costs for in-person or online registration:

  • Regular attendees: $200
  • ASCCT members: $125
  • Students/post-docs: $75
  • Undergraduate students, invited speakers: Free

In-person attendance includes all sessions, CE course, reception, dinner 1 night, breakfasts and lunches as needed. 

Online attendance includes access to participate in the oral and flash poster sessions live and view uploaded posters in the online program. Online registrants will receive links to join the oral and flash poster sessions by Zoom a few days in advance of the conference. Please add the sessions you would like to attend to your calendar via the online program.

REFUNDS: Registration refunds requested by October 7 will be allowed less a 3% administrative fee. We encourage you to consider online attendance if you are unexpectedly unable to travel.

Please direct questions to info@ascctox.org



Abstract Submission


Abstract submission is closed! Thank you for your submissions, and we look forward to your participation.


Mini CE Course


Weighing the evidence in safety evaluation and risk assessment: Data considerations and the potential for NAM integration

Friday, October 21
8:00-9:30 AM


Nikaeta Sadekar, Research Institute for Fragrance Materials
Anna Lowit, US Environmental Protection Agency

Learning Goals:
The attendees will learn about the key data attributes (e.g., quality, integrity, value, robustness, and relevance to humans) taken into consideration when evaluating data for the purpose of conducting a risk assessment. Attendees will then hear about the different decision contexts that influence the planning phase of the risk assessment. Finally, attendees will consider the influence of these decision contexts on how NAMs contribute to the weight-of-evidence in risk assessments. 

The weight of evidence (WoE) is a concept used in safety and risk assessment to describe how information from several sources are used in combination. In safety evaluation and risk assessment, a significant amount of time is spent evaluating data quality and relative value in order to assess its “weight” and its contribution to the body of evidence. This process is guided by the decision context that is driving the risk assessment, which is collaboratively defined by risk managers, risk assessors, and other stakeholders during the planning phase. In this course we will review important concepts taken into consideration when data are weighted and evaluated. The concepts of data quality, integrity, internal and external validity, and relevance to humans will be discussed using real-world case studies covering different decision contexts that highlight risk assessment frameworks that inform decision-making in both government and industry. Finally, this course will provide researchers and scientists using computational and cellular approaches with improved knowledge of the data requirements and expectations for NAM characterization, validation, and application as seen by safety and risk assessors.

Select this course when you register. Attendance is free but prior registration is appreciated.



Several awards will be offered to presenters. You must notify organizers of your wish to be considered by October 1st. Visit the online program for more information. 



Thank you to the following institutions for supporting the meeting!









Sponsorship Opportunities


Please consider supporting the meeting to help cover the expenses of an in-person meeting and give you an opportunity to promote your activities or services. The ASCCT 11th Annual Meeting sponsorship prospectus is available to download through Oxford Abstracts here.




The meeting will be held at the Sheraton Chapel Hill, located between Chapel Hill and Durham, NC. The hotel features renovated rooms and meeting, fitness, and outdoor spaces. To book your lodging within the room block offered to conference attendees, call the hotel and ask for the  ASCCT Oct. 2022 block. The nightly rate is $139 + tax, and the deadline to book within this block is September 28th. You can also make reservations by following this link: https://www.marriott.com/event-reservations/reservation-link.mi?id=1657675910148&key=GRP&app=resvlink.

Sheraton Chapel Hill
One Europa Drive
Chapel Hill, NC, 27517
+1 919-968-4900




COVID-Related Policies

Please visit the online program for the most up-to-date information, and links, on how to "Clear" yourself for the meeting: https://virtual.oxfordabstracts.com/#/event/3199/information.

The code for our event in the CLEAR app is EFATTENDEE119.

In order to minimize the potential spread of the COVID-19 virus during the meeting, we are implementing several practices, including striving for larger distancing between attendees, booking larger meeting rooms, and increasing ventilation. We also strongly recommend attendees wear appropriate and effective masks and will provide masks during the meeting.

Additionally, all attendees will be required to show a “green” health pass from the Clear app in order to obtain their badge at the meeting. A “green” designation is awarded in the following circumstances:

  • An individual has received at least 2 doses of an FDA-authorized vaccination against COVID-19*


  • an individual provides a negative PCR test result within 48 hours of arrival


  • an individual completes a symptom self-check before arrival, and commits to completing a self-check every morning.


The app allows for you to provide proof of vaccination or negative testing status without sharing any personal information with conference organizers. By registering for and attending the in-person conference, you agree to these guidelines. You also agree to conduct a symptom self-check every morning of the meeting and to avoid attendance if you experience new symptoms which might be associated with COVID-19. If you arrive without a green pass or paper copies of your vaccination certification and/or test results, you will be invited to attend the meeting virtually.

* This guidance applies to COVID-19 vaccines authorized for use and for emergency use by the U.S. Food and Drug Administration (i.e., Pfizer-BioNTech, Moderna, and Johnson and Johnson (J&J)/Janssen COVID-19 vaccines), and COVID-19 vaccines authorized for emergency use by the World Health Organization (WHO) (i.e. Pfizer-BioNTech, Moderna, and Johnson and Johnson (J&J)/Janssen, Oxford/AstraZeneca, Covishield, Covaxin, Sinopharm/BBIBP-CorV, and Sinovac/CoronaVac). The full list of vaccines with final WHO EUL/PQ evaluation status is available here.


Organizing Committee


Dave Allen, Inotiv
Dan Bagley, Vista Toxicology LLC
Sudin Bhattacharya, Michigan State University
Ellen Berg, Altopredict
Enrica Bianchi, Corteva
Amy Clippinger, PETA Science Consortium International
Eva-Maria Collins, Swarthmore College
Stephen Edwards, RTI International
Ron Filler, Drug Development Consultants
Suzanne Fitzpatrick, US FDA
Marie Fortin, Jazz Pharmaceuticals
Jack Fowle, Science to Inform
Erin Hill, IIVS
Helena Kandarova, ESTIV
Jacob Larson, Herbalife
Jan Lichtenberg, InSphero
Shaun McCullough, US EPA
Anax Oliveira, Lhasa Limited
Jessica Ponder, PCRM
Terry Riss, Promega
Nikaeta Sadekar, RIFM
Tim Shafer, US EPA
Ruchir Shah, Sciome
Alysha Simmons, UNC Chapel HIll
Kristie Sullivan, PCRM
Phoebe Woodruff, PCRM
Hao Zhu, Rutgers University