Upcoming Webinar

Using NAMs in Risk Assessment



Georges Kass’ slides



Additional resources and publications:

EPA Toxicology databases

Astuto, M.C. et al. (2022). In Silico Methods for Environmental Risk Assessment: Principles, Tiered Approaches, Applications, and Future Perspectives. In: Benfenati, E. (eds) In Silico Methods for Predicting Drug Toxicity. Methods in Molecular Biology, vol 2425. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1960-5_23

Carl Westmoreland, Hans J. Bender, John E. Doe, Miriam N. Jacobs, George E.N. Kass, Federica Madia, Catherine Mahony, Irene Manou, Gavin Maxwell, Pilar Prieto, Rob Roggeband, Tomasz Sobanski, Katrin Schütte, Andrew P. Worth, Zvonimir Zvonar, Mark T.D. Cronin,
Use of New Approach Methodologies (NAMs) in regulatory decisions for chemical safety: Report from an EPAA Deep Dive Workshop, Regulatory Toxicology and Pharmacology, Volume 135, 2022, 105261, ISSN 0273-2300, https://doi.org/10.1016/j.yrtph.2022.105261.

Ly Ly Pham, Sean M. Watford, Prachi Pradeep, Matthew T. Martin, Russell S. Thomas, Richard S. Judson, R. Woodrow Setzer, Katie Paul Friedman,
Variability in in vivo studies: Defining the upper limit of performance for predictions of systemic effect levels, Computational Toxicology, Volume 15, 2020, 100126, ISSN 2468-1113, https://doi.org/10.1016/j.comtox.2020.100126.

Prachi Pradeep, Katie Paul Friedman, Richard Judson, Structure-based QSAR models to predict repeat dose toxicity points of departure, Computational Toxicology, Volume 16, 2020, 100139, ISSN 2468-1113, https://doi.org/10.1016/j.comtox.2020.100139.

Serafimova R, Coja T and Kass GEN (2021) Application of the Threshold of Toxicological Concern (TTC) in Food Safety: Challenges and Opportunities. Front. Toxicol. 3:655951. doi: 10.3389/ftox.2021.655951