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EPIC Webinar Series on the Use of NAMs in Risk Assessment
A webinar series co-organised by the US Environmental Protection Agency, PETA Science Consortium International, the Institute for In Vitro Sciences, and the California Department of Pesticide Regulation (EPIC).

Webinar 8: Using NAMs under TSCA: a guide to EPA’s TSCA NAMs list and assessing carcinogenicity under TSCA using the ReCAAP weight of evidence framework

September 22, 2026
11:00 am ET / 15:00 UTC

Natalia Garcia-Reyero Vinas, PhD, DABT, US Environmental Protection Agency (EPA), Office of Chemical Safety and Pollution Prevention (OCSPP)
Anthony Luz, PhD, US Environmental Protection Agency (EPA), Office of Pollution Prevention and Toxics (OPPT)

Presentation Summaries

Dr. Garcia-Reyero Vinas will present the U.S. Environmental Protection Agency’s updated list of New Approach Methods (NAMs), highlighting its role in advancing chemical safety and reducing animal testing under the Toxic Substances Control Act (TSCA). EPA is also introducing a process for researchers, companies, and other stakeholders to nominate NAMs for consideration in chemical assessments. The webinar will emphasize EPA’s ongoing commitment to replacing the use of animal testing.

Dr. Luz will provide an overview of the Rethinking Carcinogenicity Assessment for Agrochemicals Project (ReCAAP) weight of evidence framework for assessing the need for carcinogenicity studies for chemicals being assessed under the Toxic Substances Control Act (TSCA). Unlike other regulatory frameworks, the TSCA Existing Chemicals Program does not mandate toxicity testing. However, TSCA does require EPA to consider all available toxicological information and make decisions based on the best available science. This webinar will explore how carcinogenicity can be assessed under TSCA in the absence of two-year rodent carcinogenicity studies, including real-world examples of ReCAAP application.